Scientific Pubblications


Light emitted from different sources plays the leading role in the treatments developed by Dr. Roberto Pinelli and proposed by the Switzerland Eye Research Institute in Lugano.

Vision deficiencies (myopia, hypermetropia and astigmatism) can be resolved with a safe and non-invasive treatment using photons, Femtolasik Lux®.

Presbyopia also benefits from a version of this technique,based on an algorithm called the Pinelli Presby Profile® .

Transepithelial osmotic crosslinking with ultraviolet light and  ParaCel® eye drops halts the progression of keratoconus.

Photobiomodulation of the mitochondria of the macula photoreceptors is beneficial to the dry form of macular degeneration.

Nutraceuticals nourish the retina with natural and extremely pure plant substances.

Peer-reviewed scientific publications in international journals have confirmed the validity of the proposal for a non-invasive ophthalmology, free of side effects, which envisages the use of photons in a future full of light.

This prestigious molecular biology journal has recently published a multicenter study of a new approach to the pathogenesis of macular degeneration. The peer-reviewed scientific paper – the fruit of extensive and painstaking research – highlights the important role played by the first retinal layer, the pigmented epithelium, in the genesis of retinal disease and its virtuous relationship with certain phytochemicals. The term “phytochemicals” refers to substances with intrinsically chemical properties that are non-synthetic (i.e. not produced in the laboratory) but rather are derived directly from natural plant substances. The role played by these substances confirms that sound scientific principles lie behind nutraceutics, and that its use in ophthalmology is invaluable in the metabolic and catabolic processes of photoreceptors.


In this scientific article published in June 2020 in “Archives Italiennes de Biologie”, the world’s oldest neuroscience journal, a clinical case is reported of AMD (age-related macular degeneration), also known as senile macular degeneration or senile daculopathy. We demonstrated a marked improvement in retinal tissue after six months of dietary supplementation with lutein, resveratrol and blueberry in specific doses.

The publication, which emerged from a multicentre collaborative project, demonstrates the validity of the use of specific nutraceutical substances that have proven effective in the treatment of eye diseases.

The support of nutraceuticals could provide a non-invasive and side-effect-free treatment for retinal disease. The results of this study were examined with a view to assessing the synergy of molecular mechanisms in progress in the anatomical structure positioned between the retina and the choroid.

These findings are also clearly visible in the images accompanying the article, which bears the names of Dr. Roberto Pinelli and his co-workers (Dr. Miorica Bertelli and Dr. Elena Scaffidi) of the Switzerland Eye Research Institute of Lugano; Dr. Federica Fulceri of the University of Pisa (Department of Clinical and Experimental Medicine); Dr. Maico Polzella of the Aliveda Laboratories of Pisa, Dr. Francesca Biagioni of the Neuromed Clinical Research Institute of Isernia; and Prof. Francesco Fornai of the University of Pisa (Department of Translational Research and New Technologies in Medicine and Surgery).

This publication heralds the transition of maculopathy research from the field of ophthalmology to that of neuroscience (the retina being a nervous tissue).


The Lugano Protocol is the name of the project developed by Dr. Roberto Pinelli of the Switzerland Eye Research Institute, which offers an effective treatment for maculopathy, the world’s leading cause of blindness.

The renowned American scientific journal CellR4 has published the results of the all-natural combination of photons (light particles) and nutraceuticals acting on AMD (Age-related Macular Degeneration).

The journal, which specialises in cell regeneration, presented the first case in the world concerning clinical regression of maculopathy that does not involve surgery. Instead, it acts through the synergy between photobiomodulation to reactivate the cellular mitochondria of the retina, and nutraceuticals.

The author of the study, Roberto Pinelli, founder and scientific director of SERI Lugano, stated: “We are delighted with the publication of our results in the authoritative scientific publication CellR4, a journal which focuses on cell regeneration. Our results show that retinal cells can be stimulated by a new non-invasive approach that combines the power of light with substances obtained entirely from plants”.

This publication is further confirmation of our country’s drive for innovation.


On the cover of the prestigious American publication Ophthalmology Times, Roberto Pinelli’s article on his Femtolasik Lux® technique was presented in a special edition: “Procedures set a new horizon in refractive surgery”. A special tribute to the pioneering use of light in the correction of visual defects, the founder and scientific director of the Switzerland Eye Research Institute in Lugano, and his team of specialists.


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